Music Almanac: September 21
- 1921 - Jimmy Young (91)
- 1932 - Don Preston (session musician) (80)
- 1934 - Leonard Cohen (78)
- 1936 - Dickey Lee (born Royden Lipscomb) (76)
- 1941 - Dante Moon (Dante & the Evergreens) (71)
- 1947 - Don Felder (Eagles) (65)
- 1952 - Kenny Starr (60)
- 1953 - Betty Wright (59)
- 1959 - Phil Taylor (Motorhead) (53)
- 1959 - Corinne Drewery (Swing Out Sister) (53)
- 1967 - Faith Hill (45)
- 1967 - Tyler Stewart (Barenaked Ladies) (45)
- 1967 - Timmy T (born Timothy Tores) (45)
- 1968 - Jon Brookes (Charlatans) (44)
- 1968 - Trugoy (born David Jude Jolicoeur) (De La Soul) (44)
- 1972 - Liam Gallagher (Oasis) (40)
- 1972 - David Silveria (Korn) (40)
- 1973 - Jimmy Constable (911) (39)
- 1977 - Sam Rivers (Limp Bizkit) (35)
- 1986 - Faris Rotter (Horrors) (26)
Deaths
- 1974 - Walter Brennan - Emphysema (80)
- 1987 - Jaco Pastorius (Weather Report, Blood, Sweat & Tears) - Brain hemorrhage after being beaten (35)
- 2006 - Boz Burrell (King Crimson, Bad Company) - Heart attack (60)
- 1965 - The Moody Blues play their first major show at London's Royal Albert Hall.
- 1974 - Jeff “Skunk” Baxter joined the Doobie Brothers.
- 1980 - Bob Marley collapsed during a run in New York's Central Park. The ensuing examination showed that he was suffering from cancer.
- 1980 - Elton John signed with Geffen Records.
- 1986 - Britain's National Inquirer reported about Michael Jackson's goal of living to 150 and showed a picture of him in an oxygen chamber.
- 1989 - The Bangles announced that they were splitting up.
- 1991 - Status Quo played four cities (Sheffield, Glasgow, Birmingham, London) in one day, setting a record.
- 1996 - Hank Williams III made his debut at the Grand Ole Opry.
- 1999 - Melissa Auf Der Maur left Hole.
- 1999 - Diana Ross was arrested at London's Heathrow Airport for assaulting a guard.
- 2000 - Genesis reunited for one night at the British Music Roll of Honour show.
- 2000 - Bono was on Capitol Hill in Washington pushing his debt relief plan for third world nations.
- 2000 - Barenaked Ladies received the key to Toronto.
- 2002 - Farm Aid '02 was held in Burgettstown, PA with Willie Nelson, Neil Young, John Mellencamp, Dave Matthews, Keith Urban, Lee Ann Womack, Kid Rock, Gillian Welch, Kenny Wayne Shepherd with Double Trouble, The Drive-By Truckers, Los Lonely Boys and Anthony Smith
- 2004 - Yusuf Islam (formerly Cat Stevens) was denied entrance into the U.S. when his name turned up on an anti-terrorist watch list.
- 2007 - Snoop Dogg received three years probation and 150 hours of community service for carrying a collapsible baton.
- 1968 - All Along the Watchtower - Jimi Hendrix (single)
- 1974 - You Ain't Seen Nothin' Yet - Bachman-Turner Overdrive (single)
- 1976 - Children of the World - Bee Gees
- 1984 - Tonight - David Bowie
- 1992 - Yes Please - Happy Mondays (last release for Factory Records
- 1992 - Creep - Radiohead (single)
- 1993 - In Utero - Nirvana
Broadcasts
- 1971 - Old Grey Whistle Test (debut) - America, Lesley Duncan
- 1972 - In Concert (ABC) (debut) - Alice Cooper
- 1984 - Burning Rage (Made for TV Movie) - Barbara Mandrell (acting debut)
- 1999 - Reverb (MTV) (debut) - Alanis Morissett, Everlast
- 2001 - America: A Tribute to Heroes (35 Different Networks)
- 1946 - To Each His Own - Ink Spots (1 week)
- 1959 - Sleep Walk - Santo & Johnny (2 weeks)
- 1963 - Blue Velvet - Bobby Vinton (3 weeks)
- 1968 - Harper Valley P.T.A. - Jeannie C. Reiley (1 week)
- 1974 - Can't Get Enough of Your Love, Baby - Barry White (1 week)
- 1985 - Money for Nothing - Dire Straits (3 weeks)
- 1991 - I Adore Mi Amor - Color Me Bad (2 weeks)
Number Ones –
U.S. Albums
- No albums made number 1 in the U.S. on September 21.